An Epidemic of Thyrotoxicosis

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Frederic Shaw and Richard Dicker
Date published
Dec, 2003
Last updated
21 Jan 2020


Outbreak with unknown etiology and mode of transmission, crossing state lines, 1985; a nice wrap-up study, domestic U.S. focus.


  • Define and perform calculations of sensitivity, specificity, predictive-value of a positive test, and predictive-value of a negative test
  • Describe the relationship between prevalence and predictive value
  • Discuss the trade-offs between sensitivity and specificity
  • List the principles of a good screening program