Measles Outbreak in Highly Vaccinated Population

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Robert Chen, Bernard Morniere and Richard Dicker
Date published
Jan, 1991
Last updated
22 Jan 2020


An outbreak of measles occurred in health sector Muyinga (Burundi), several years into an apparently successful vaccination program.  This case study addresses estimation of vaccine coverage and vaccine efficacy in the field.  

Learning Objectives:

After completeing this case study, the participant should be able to:

  • Discuss methods for estimating vaccination coverage;
  • Describe the difference between a convenience sample and a probability sample;
  • Describe the sampling method used in WHO-EPI surveys; and
  • Calculate and interpret vaccine efficacy.