Oral Contraceptive Use and Ovarian Cancer

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Richard Dicker and Peter Layde
Date published
Dec, 2002
Last updated
21 Jan 2020


One of the first studies to address the association between oral contraceptive use and ovarian cancer was conducted by the Centers for Disease Control and Prevention (CDC) using a multicenter case-control study design, 1980‑1982.


  • List the elements needed for informed consent in an epidemiologic study
  • Outline the sequence of an epidemiologic analysis
  • Discuss the biases of particular concern in case-control studies and ways to minimize their influence
  • Describe why and when to use crude and adjusted odds ratios and 95% confidence intervals, and how to interpret them
  • Define and recognize effect modification and confounding